Magnesium
Magnesium is a moderate-risk supplement with an RDA of 420 mg and a tolerable upper intake level (UL) of 350 mg per day according to NIH/NASEM standards. EFSA lists the same RDA but a UL of 250 mg; CNS lists a RDA of 330 mg but has not established a formal UL; MHLW lists a RDA of 340 mg with the same UL. It has 1 known interaction with other supplements including vitamin b6. Use NutriAudit to check if your supplement stack keeps this ingredient within safe limits.
Quick take
Magnesium sits in the Major Minerals category. This page consolidates 5 regional standards, and the limits vary enough that you should not treat one region's rule as universal.
It also has 1 known interaction, so the question is not just the label dose but whether the rest of your stack adds extra risk.
Taking multiple supplements? Check Magnesium for overlap
If Magnesium appears on two product labels, enter each daily amount and check the combined label total.
Check Magnesium across my supplementsFree. No account required.
Overdose Risk Warning
Excess magnesium often causes diarrhea; very high doses can affect heart rhythm in susceptible people.
Regional Reference Values
| Region | Organization | RDA | Upper Limit (UL) | Unit |
|---|---|---|---|---|
| 🇺🇸 United States | NIH Office of Dietary Supplements | 420 | 350 | mg |
| 🇪🇺 Europe | European Food Safety Authority | 420 | 250 | mg |
| 🇦🇺 Australia | NHMRC / Eat For Health | 420 | 350 | mg |
| 🇨🇳 China | 国家卫健委 WS/T 578.2—2018 | 330 | Not established | mg |
| 🇯🇵 Japan | MHLW Dietary Reference Intakes for Japanese 2025 | 340 | 350 | mg |
China: The cited standard does not establish an adult magnesium UL.
RDA = Recommended Daily Allowance (adequate intake for most adults). UL = Tolerable Upper Intake Level; some authorities have not established one.
Known Interactions
Vitamin B6 and magnesium work synergistically (positive interaction).
Taking together may enhance effectiveness.
How to use this page
First match your product label against the dose table above, then check whether the known interaction list includes anything in your current stack.
If you are taking multiple supplements, the safest approach is usually to audit the whole stack instead of judging a single bottle in isolation.
Frequently Asked Questions
How much Magnesium is too much?
NIH Office of Dietary Supplements lists a formal upper limit (UL) of 350mg per day for Magnesium. Other regions may use a different value or have no established UL.
What is the recommended daily dose of Magnesium?
The RDA for Magnesium is 420mg per day for most adults. This amount is sufficient to meet the needs of 97-98% of healthy individuals.
Does Magnesium interact with other supplements?
Yes, Magnesium has 1 known interaction with other supplements. Vitamin B6 and magnesium work synergistically (positive interaction).
Are you taking Magnesium?
Check if your supplement stack keeps Magnesium within safe limits.
Audit My SupplementsDisclaimer: NutriAudit is a decision-support tool designed to help you review your supplement stack for potential duplicate, conflicting, or excessive ingredients. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making changes to your supplement routine, especially if you are pregnant, nursing, taking medications, or have a medical condition.
Uses cited public reference data where the current dataset has a verified entry.